Extract of Ganoderma lucidum prolongs sleep time in rats

Abstract Ethnopharmacological relevance: Ganoderma lucidum (Ling Zhi) is a basidiomycete white-rot macrofungus that has been used as a tranquilizing agent (i.e., An-Shen effect) for the treatment of restlessness, insomnia, and palpitation in China for hundreds of years. Aim of the study: The present study aimed to investigate whether Ganoderma lucidum extract (GLE) influences the sleep of freely […]

Continue Reading

High blood pressure

Signs and Symptoms Most people do not know they have high blood pressure because they have no symptoms. Rarely, some people may have a mild headache when their blood pressure is high. Advanced cases of hypertension may cause these symptoms: Severe headache Confusion Nausea Visual disturbances Seizure Causes There are two major types of high […]

Continue Reading

Chemical, biochemical, preclinical and clinical studies of Ganoderma lucidum polysaccharide as an approved drug for treating myopathy and other diseases in China

Ganoderma lucidum is an edible medicinal mushroom known as “Lingzhi” in China and “Reishi or Manetake” in Japan. It is a highly prized vitality‐enhancing herb for more than 2000 years. G. lucidum polysaccharide (GLPS) has been identified as one of the major bioactive components and developed into a drug named “Ji 731 Injection” in China since 1973. The large‐scale production […]

Continue Reading

Probing Lingzhi or Reishi medicinal mushroom Ganoderma lucidum (higher Basidiomycetes): a bitter mushroom with amazing health benefits

Abstract Ganoderma lucidum (Lingzhi or Reishi) is known as a bitter mushroom with remarkable health benefits. The active constituents found in mushrooms include polysaccharides, dietary fibers, oligosaccharides, triterpenoids, peptides and proteins, alcohols and phenols, mineral elements (such as zinc, copper, iodine, selenium, and iron), vitamins, and amino acids. The bioactive components found in the G. […]

Continue Reading

The antifungal effects of alcoholic extract of Ganoderma lucidum on candida isolates

Abstract Introduction: Candidiasis is a common fungal infection caused by various species of the Candida. Candida albicans is the most important etiologic agent of candidiasis which includes about 60%-75% of this disease. The extent of fungal opportunistic infections in susceptible individuals on one hand and increasing drug resistance on the other hand, leads to the […]

Continue Reading

Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), Inhibits Candida Biofilms: A Metabolomic Approach

Abstract This article presents a comparative gas chromatography (GC)-mass spectrometry (MS)-based metabolomic analysis of mycelia and fruiting bodies of the medicinal mushroom Ganoderma lucidum. Three aqueous extracts-mycelia, fruiting bodies, and a mixture of them-and their sequential fractions (methanolic and ethyl acetate), prepared using an accelerated solvent extractor, were characterized by GC-MS to determine volatile organic […]

Continue Reading

Suppression of inflammatory and allergic responses by pharmacologically potent fungus Ganoderma lucidum

Abstract Acute inflammation is the result of a complex signal transduction pathway that protects and heals our body and is necessary for our good health and normal wellbeing. Whereas, chronic inflammation can be correlated well with the onset of a plethora of autoimmune disorders; rheumatoid arthritis, systemic lupus and polymyalgia, rheumatic and other diseases like […]

Continue Reading

Cordyceps Polysaccharides

Abstract Cordyceps, parasitic fungi grown on the larva of caterpillar, is a unique and precious edible and medicinal herb in Traditional Chinese Medicine (TCM), and has long been used in traditional therapies. Polysaccharide, one of the bioactive constitutents of Cordyceps, exhibits a wide range of bioactivities. In recent years, with the development of agamotype and submerged […]

Continue Reading