Month: May 2022

An employee processes Cordyceps flowers on the production line at a fungus company on August 7, 2020, in Suining, China. Liu Changsong/VCG via Getty Images Researchers recently modified a metabolite derived from a Himalayan fungus. They believe it may help treat cancer. Early results suggest that the modified fungal metabolite is well tolerated in people with advanced […]

Abstract Cordyceps is a genus of ascomycete fungi that has been used for traditional herbal remedies. It contains various bioactive ingredients including cordycepin. Cordycepin, also known as 3-deoxyadenosine, is a major compound and has been suggested to have anticancer potential. The treatment of various cancer cells with cordycepin in effectively induces cell death and retards their […]

A new industry-academic partnership between the University of Oxford and biopharmaceutical company NuCana as found that chemotherapy drug NUC-7738, derived from a Himalayan fungus, has 40 times greater potency for killing cancer cells than its parent compound. Oxford University researchers have worked in collaboration with industry leaders NuCana to assess a novel chemotherapy drug derived […]

Abstract This study was aimed to investigate the antihypertensive effect of a polysaccharide fraction from Cordyceps sinensis on spontaneously hypertensive rats (SHR). The CSP1, one component of Cordyceps sinensis polysaccharides (CSP), was obtained after water extraction, deproteinization, de-colorization and purification with DEAE-cellulose 52. And a more homogeneous component CSP1-2 was obtained using Sepharose CL-6B chromatography. […]

Cordyceps is a type of medicinal mushroom said to offer antioxidant and anti-inflammatory benefits. Long used in traditional Chinese medicine, cordyceps is available in the United States as a dietary supplement.   There are 400 species of cordyceps, most of which are native to Bhutan, China, Korea, Nepal, Thailand, and Vietnam. The most well-known medicinal species is Cordyceps […]

Abstract An unknown antibiotic, ophiocordin, C21H22N2O8, MW: 430, was isolated from submerged cultures of Cordyceps ophioglossoides, strain TÜ 276, grown in a glycerol soybean meal medium at 27°C. The antibiotic was extracted from acidified culture fluids with n-butanol and purified by subsequent column chromatography on DEAE-Sephadex and cellulose. Studies including nuclear magnetic resonance and mass spectrometry […]

Abstract Natural Cordyceps sinensis, which is a valuable anti-tumor, immunomodulatory, and antiviral agent in Asia, has been overexploited in recent years. Therefore, it is important for cultivated C. sinensis to be recognized in the market. In this research, the main components of entirely cultivated, naturally grown C. sinensis, and stiff worms across different sampling years were detected and compared by HPLC-MS […]

December 8, 2019 Medicinal mushrooms are everywhere these days, from tinctures and pills to coffee and moisturizers. While they’re definitely having a moment, mushrooms are nothing new; many have been used in ancient medicine for millennia. There are thousands of species of mushrooms, and their purported benefits range from supporting liver and heart health to […]

Abstract The immune-modulatory as well as anti-influenza effects of Cordyceps extract were investigated using a DBA/2 mouse model. Three different concentrations of Cordyceps extract, red ginseng extract, or drinking water were orally administered to mice for seven days, and then the mice were intranasally infected with 2009 pandemic influenza H1N1 virus. Body weight changes and […]