Tremella Archives - Medicinal Mushroom Clinical Research, News and Recipes

Tremella fuciformis Crude Polysaccharides Attenuates Steatosis and Suppresses Inflammation in Diet-Induced NAFLD Mice

April 1, 2022April 1, 2022Ijaz

Guangdong Provincial Key Laboratory of Infectious Diseases and Molecular Immunopathology, Shantou University Medical College, Shantou 515041, ChinaGeometry Cell Biology Research Center, Dongguan 523808, ChinaThe Center for Reproductive Medicine, Shantou University Medical College, Shantou 515041, ChinaAuthor to whom correspondence should be addressed. Abstract Nonalcoholic fatty liver disease (NAFLD) is a chronic liver disorder characterized by an […]

The anti-obesity effect of fermented tremella/blueberry and its potential mechanisms in metabolically healthy obese rats

April 1, 2022April 1, 2022Ijaz

Highlights • A metabolically healthy obesity (MHO) rat model was established in this study. • The anti-obesity potential of fermented Tremella/blueberry (FTB) was evaluated. • FTB reduced body weight and improved lipid profiles of MHO rats. • FTB modulated the diversity of gut microbiota and metabolites profile. Abstract Fermented fruits or vegetables has attracted much attention by […]

Chapter Sixteen – Tremella polysaccharide: The molecular mechanisms of its drug action

April 1, 2022April 1, 2022Ijaz

Abstract Tremella fuciformis is an edible medicinal mushroom well known as “Yiner” or “Baimuer” in China and has been used as a Chinese herb for many years. T. fuciformis polysaccharide (TFPS) has been identified as a major bioactive component. Different experimental conditions can obtain different TFPS fractions, which makes TFPS a mixture of different polysaccharides […]

Tremella polysaccharides inhibit cellular apoptosis and autophagy induced by Pseudomonas aeruginosa lipopolysaccharide in A549 cells through sirtuin 1 activation

March 31, 2022March 31, 2022Ijaz

Abstract In the present study, the role of Tremella polysaccharides in cellular apoptosis and autophagy induced by Pseudomonas aeruginosa lipopolysaccharide (LPS) in human epithelial A549 lung-cancer cells was investigated. Initially, it was demonstrated that LPS attenuated A549 cell viability in a time- and dose-dependent manner. Furthermore, LPS induced apoptotic cell death and autophagy in A549 cells and increased reactive […]

The hypocholesterolemic effect of two edible mushrooms: Auricularia auricula (tree-ear) and Tremella fuciformis (white jelly-leaf) in hypercholesterolemic rats

March 31, 2022March 31, 2022Ijaz

Abstract The effect of two edible mushrooms, namely Auricularia auricula (Tree-ear) and Tremella fuciformis (White jelly-leaf) of the Heterobasidiae, on serum and liver lipids, fecal neutral steroids and bile acid excretion was investigated in rats. Male Sprague-Dawley rats were fed two semisynthetic hypercholesterolemic diets (1.5% cholesterol, 5% fat) each containing 5% dried powder of the two mushrooms. After 4 wk […]

Tremella fuciformis polysaccharide suppresses hydrogen peroxide-triggered injury of human skin fibroblasts via upregulation of SIRT1

March 31, 2022July 4, 2022Ijaz

Abstract Tremella fuciformis polysaccharide (TFPS), which is the extract of Tremella fuciformis Berk, has previously been demonstrated to exhibit potent anti-oxidative, anti-inflammatory and anti-aging effects. However, the mechanisms underlying these protective and therapeutic effects remain to be elucidated. The aim of the present study was to investigate the protective effects of TFPS on hydrogen peroxide-induced injury of human […]

Tremella fuciformis Polysaccharides Attenuate Oxidative Stress and Inflammation in Macrophages through miR-155

March 31, 2022March 31, 2022Ijaz

Abstract Aim: To investigate the function of Tremella fuciformis polysaccharides (TFPS) in LPS-induced inflammation and oxidative stress of macrophages. Methods: RAW264.7 cells were pretreated with TFPS and then stimulated with 0.1 μg/ml LPS. NFκB, Akt, p38MAPK, MCP-1, and SOD-1 were analyzed by Western blotting. Cell viability was measured using MTT assays. Reactive oxygen species (ROS) production, real-time PCR, ELISA, and […]