Anti-inflammatory activity on mice of extract of Ganoderma lucidum grown on rice via modulation of MAPK and NF-╬║B pathways

Abstract Ganoderma lucidum is a popular medicinal mushroom with anti-inflammatory potential. In the present study, the aim was to determine the anti-inflammatory effect and mode of action of G. lucidum grown on germinated brown rice (GLBR) in a mouse model of colitis. It was shown that GLBR suppressed the production of nitric oxide (NO) and […]

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CNS anti-depressant, anxiolytic and analgesic effects of Ganoderma applanatum (mushroom) along with ligand-receptor binding screening provide new insights: Multi-disciplinary approaches

Highlights The mushroom extracts were found to possess dose-dependent potentiality in antidepressant and anxiolytic test on mice model. The mushroom extracts revealed significant inhibition in pain. The mushroom extract is non-toxic evident from acute toxicity study. Ganoderma applanatum can be a prominent source of CNS depressant, anxiety and pain management. Ganoderma applanatum┬áis a bracket fungus […]

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