Maitake D Fraction Hepatitis Research

Hepatitis (meaning an inflammation of the liver) is caused by several different viruses. Hepatitis A is spread through contaminated water and food and is excreted in the stools. Hepatitis B is acquired from transfusions or other blood products. It can be transmitted through minute cuts or abrasions or by such simple acts as kissing, tooth […]

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Inhibition of hepatitis B virus by D-fraction from Grifola frondosa: Synergistic effect of combination with interferon-α in HepG2 2.2.15

In this study, D-fraction extracted from Grifola frondosa (GF-D) and its combination with human interferon alpha-2b (IFN) were investigated for the inhibitory effect on hepatitis B virus (HBV) in HepG2 2.2.15 cells (2.2.15 cells). HBV DNA and viral antigens were analyzed by a quantitative real-time polymerase chain reaction and end-point titration in radioimmunoassays, respectively. The […]

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The Impact of Mushroom Polysaccharides on Gut Microbiota and Its Beneficial Effects to Host: A Review

Mushroom polysaccharides are a type of bioactive macromolecular which isolated from fruiting bodies, mycelia or fermentation broths of edible or medicinal fungus. Recently, mushroom polysaccharides have attracted a lot of attention for regulating gut microbiota via reducing the levels of pathogens and stimulating the growth of beneficial microorganisms, thus creating new possibilities for their use […]

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Prebiotic Effect of Maitake Extract on a Probiotic Consortium
and Its Action after Microbial Fermentation on Colorectal
Cell Lines

Abstract: Maitake (Grifola frondosa) is a medicinal mushroom known for its peculiar biologicalactivities due to the presence of functional components, including dietary fibers and glucans, thatcan improve human health through the modulation of the gut microbiota. In this paper, a Maitakeethanol/water extract was prepared and characterized through enzymatic and chemical assays. Theprebiotic potential of the […]

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Hypoglycemic activity and gut microbiota regulation of a novel polysaccharide from Grifola frondosa in type 2 diabetic mice

Abstract GFP-N, a novel heteropolysaccharide with a molecular weight of 1.26 × 107 Da, was isolated from maitake mushroom and purified by anion-exchange chromatography on a DEAE cellulose-52 column and gel-filtration chromatography on a Sephadex G-100 column. Its structure was characterized by Fourier transform infrared spectroscopy and one-dimensional (1H- and 13C-) NMR spectra, 1H1H correlation spectroscopy, and 1H13C heteronuclear […]

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A Critical Review on Health Promoting Benefits of Edible Mushrooms through Gut Microbiota

Abstract Mushrooms have long been used for medicinal and food purposes for over a thousand years, but a complete elucidation of the health-promoting properties of mushrooms through regulating gut microbiota has not yet been fully exploited. Mushrooms comprise a vast, and yet largely untapped, source of powerful new pharmaceutical substances. Mushrooms have been used in […]

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Maitake Mushroom

For Patients & Caregivers Tell your healthcare providers about any dietary supplements you’re taking, such as herbs, vitamins, minerals, and natural or home remedies. This will help them manage your care and keep you safe. Maitake demonstrated anticancer effects in laboratory studies. Research is underway to test its anticancer effects in humans. Maitake is a […]

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Anti-diabetic effect of an alpha-glucan from fruit body of maitake (Grifola frondosa) on KK-Ay mice

Abstract We have evaluated the anti-diabetic effect of a alpha-glucan (MT-alpha-glucan) from the fruit body of maitake mushrooms (Grifola frondosa) on KK-Ay mice (a kind of genetical type 2 diabetes animal model). The effects of MT-alpha-glucan (450 or 150 mg kg (-1)) on diabetic mice were investigated by observing the changes in body weight, the […]

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