A comparative study of the antimicrobial, antioxidant, and cytotoxic activities of methanol extracts from fruit bodies and fermented mycelia of caterpillar medicinal mushroom Cordyceps militaris

Cordyceps militaris is one of the most popular mushrooms and nutraceuticals in Eastern Asia. This study assayed and compared the antimicrobial, antioxidant, and cytotoxic properties of the methanol extracts from fruiting bodies and fermented mycelia of C. militaris, as well as the contents of total phenol, flavonoids, and cordycepin. The results showed that the extracts […]

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Cordyceps sinensis promotes immune regulation and enhances bacteriostatic activity of PA-824 via IL-10 in Mycobacterium tuberculosis disease

PA-824 is a novel bicyclic nitroimidazole anti-tuberculosis (TB) drug. Cordyceps sinensis (Berk.) Sacc. (CS) was proven to be a good immunomodulatory compound. This research aimed to investigate the effect of CS on PA-824 in Mycobacterium tuberculosis (M.tb) infected mice (female CBA/J mice, 6 to 8 weeks of age and 20±2 g of weight). Mice were randomly assigned to 4 […]

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Efficacy of Cordyceps militaris Extracts against Some Skin Pathogenic Bacteria and Antioxidant Activity

Cordyceps militaris has been used for treating various diseases, as well as maintaining good overall health. The antibacterial properties of the C. militaris fruiting body and substrate, cultured in Chiang Mai (sample A and B) and Chiang Rai (sample C), Thailand, were investigated in this study. The aqueous and ethanolic extracts of C. militaris exhibited antibacterial activities against Staphylococcus aureus, Pseudomonas aeruginosa, Cutibacterium […]

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Xanthine Oxidase Inhibitory Potential, Antioxidant And Antibacterial Activities Of Cordyceps Militaris (L.) Link Fruiting Body

Abstract Being Cordyceps militaris (L.) Link recognized as a medicinal and edible mushroom, this work intends to reveal new interesting bioactive molecules that could be isolated from this species. Hydrophilic and lipophilic compounds were analyzed by chromatographic techniques coupled to different detectors. The methanolic extract of C. militaris was tested for its antioxidant, antibacterial, antifungal […]

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Cordyceps sinensis Increases Hypoxia Tolerance by Inducing Heme Oxygenase-1 and Metallothionein via Nrf2 Activation in Human Lung Epithelial Cells

Cordyceps sinensis, an edible mushroom growing in Himalayan regions, is widely recognized in traditional system of medicine. In the present study, we report the efficacy of Cordyceps sinensis in facilitating tolerance to hypoxia using A549 cell line as a model system. Treatment with aqueous extract of Cordyceps sinensis appreciably attenuated hypoxia induced ROS generation, oxidation of lipids and proteins […]

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Does Cordyceps sinensis Ingestion Aid Athletic Performance?

Abstract summary  Cordyceps sinensis is a potentially ergogenic herb that gained popularity after the Chinese women’s team credited it for their world-record performances at the 1993 World Track and Field Championships. Since then, a few peer-reviewed investigations have been published, but results of these investigations have been equivocal, with two human studies claiming an ergogenic […]

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Cordyceps as an Herbal Drug

5.1. INTRODUCTION Cordyceps is the composite of a genus of fungus that grows on the larva of insects. To date, more than 350 Cordyceps-related species have been found worldwide based on fungus and/or insect host. However, since 1964, only Cordyceps sinensis has been recorded officially as an herbal drug in Chinese pharmacopoeia. C. sinensis, known as Dongchongxiacao (winter-worm summer-grass) in Chinese, is one […]

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Cordyceps Libido and Erectile Function

Cordyceps has been used for centuries by traditional Chinese medicine to help with sexual dysfunction. Preclinical data on the effects of Cordyceps on mice showed sex steroid-like effects. (Holliday, J. et al. On the Trial of The Yak Ancient Cordyceps in the Modern World. 2004) The results of human clinical trials published in The Journal Of […]

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Cordyceps as an Herbal Drug

Cordyceps is the composite of a genus of fungus that grows on the larva of insects. To date, more than 350 Cordyceps-related species have been found worldwide based on fungus and/or insect host. However, since 1964, only Cordyceps sinensis has been recorded officially as an herbal drug in Chinese pharmacopoeia. C. sinensis, known as Dongchongxiacao (winter-worm summer-grass) in Chinese, is one of the […]

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