Immunomodulatory Activity of the Water Extract from Medicinal Mushroom Inonotus obliquus

Abstract The immunomodulatory effect of aqueous extract of Inonotus obliquus, called as Chaga, was tested on bone marrow cells from chemically immunosuppressed mice. The Chaga water extract was daily administered for 24 days to mice that had been treated with cyclophosphamide (400 mg/kg body weight), immunosuppressive alkylating agent. The number of colony-forming unit (CFU)-granulocytes/macrophages (GM) and […]

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5 Reasons to Consider Chaga Mushrooms

The studies thus far on the health benefits of chaga are encouraging, though scientists say a lot more research is necessary. “Chaga can be supportive in cancer treatment. It can assist in lowering blood pressure, cholesterol, and blood sugar, and it can also help the immune system by regulating the cytokines that help increase the immune fighter cells like white blood […]

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Anti-diabetic effects of Inonotus obliquus polysaccharides in streptozotocin-induced type 2 diabetic mice and potential mechanism via PI3K-Akt signal pathway

Abstract Polysaccharides are the main components of mushroom Inonotus obliquus (I. obliquus) with antihyperglycemic activities. This study was aimed to investigate the anti-diabetic effects and the potential mechanism of I. obliquus polysaccharides (IOPS) in high fat diet and STZ-induced type 2 diabetic mice. Results showed that oral administration of IOPS (900mg/kg) could significantly restore the […]

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Choose Chaga Mushrooms?

What can you tell me about chaga? I’ve read that this mushroom can boost immunity, lower blood pressure and cholesterol levels, kill cancer cells, reduce inflammation and sharpen the mind. All true?   Chaga (Inonotus obliquus) has long been used as a folk remedy for cancer, tuberculosis, diabetes, and digestive diseases in Russia and elsewhere in […]

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Anticancer effects of fraction isolated from fruiting bodies of Chaga medicinal mushroom, Inonotus obliquus (Pers.:Fr.) Pilát (Aphyllophoromycetideae): in vitro studies

Abstract The medicinal mushroom Chaga, Inonotus obliquus (Pers.:Fr.) Pilát (Hymenochaetaceae), has been used in folk medicine in Russia, Poland, and most of the Baltic countries, as a cleansing and disinfecting measure, and as decoctions for stomach diseases, intestinal worms, liver and heart ailments, and cancer treatment. Many reports have been published concerning the health promoting […]

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Continuous intake of the Chaga mushroom (Inonotus obliquus) aqueous extract suppresses cancer progression and maintains body temperature in mice

Aims Cancer is a leading cause of morbidity and mortality worldwide; therefore, effective measures for cancer prevention and treatment are in constant demand. The extracts of Inonotus obliquus (Chaga mushroom) demonstrate potent anti-tumor activities and have been used to treat cancer in several countries; however, the actual effect and underlying mechanisms are still unclear. In the present […]

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Chaga Mushroom Health Benefits

This fungi may help reduce inflammation and lower blood sugar Sure, you’ve heard of portobello and shiitake mushrooms. But have you heard of chaga mushrooms? Typically found in Siberia, the fungi have been used throughout history to boost immunity thanks to it being full of antioxidants. So where can you find chaga mushrooms, how do […]

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Health Benefits of Chaga Tea

For centuries people in Eastern Europe have been drinking chaga tea for its many health benefits. Chaga tea is made from the chaga mushroom, which typically grows on the trunks of birch trees in the Northern Hemisphere. In North America, you will typically find it in the Northeast.The Latin name for chaga mushroom is Inonotus obliquus, […]

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