Medicinal Mushrooms (PDQ®)–Health Professional Version

Introduction Medicinal mushrooms have been used for hundreds of years, mainly in Asian countries, for treatment of infections. More recently, they have also been used in the treatment of pulmonary diseases and cancer. Medicinal mushrooms have been approved adjuncts to standard cancer treatments in Japan and China for more than 30 years and have an extensive clinical history of safe use as single […]

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Inhibition of growth and induction of apoptosis in human cancer cell lines by an ethyl acetate fraction from shiitake mushrooms

Abstract Objective: Shiitake (Lentinus edodes) mushrooms have been reported to have cancer-preventing properties. However, little research has been conducted verifying the antitumor activities of “mycochemicals” in shiitake mushrooms. In this study, potential roles of an ethyl acetate fraction from shiitake mushrooms were investigated by in vitro bioassays. Design: The activities of an ethyl acetate fraction were evaluated […]

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Shiitake Mushroom, Lentinan, and Cancer

General Information The edible mushroom Lentinus edodes is known as shiitake in Japan and xianggu in China.1 It originated in East Asia, where it grows on decaying trees and figures prominently in traditional medicine, but it is now widely cultivated around the world. It is one of several mushrooms with frequently reported but unconfirmed anticancer properties and other health benefits.2-5 […]

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Shiitake Mushroom

How It Works Small studies have evaluated shiitake mushroom extract, with mixed results. Lentinan, a polysaccharide extracted from shiitake, may help extend the survival of patients with some cancers when used with chemotherapy, but additional studies are needed. Some of the medicinal properties of shiitake mushroom are attributed to a sugar molecule named lentinan, on which extensive […]

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Explainer | Eating two mushrooms a day could lower cancer risk by 45 per cent, study finds. Experts recommend a pinch of salt

Mushrooms contain high levels of antioxidants, and chemical components believed to strengthen the immune system. A study touts their anti-cancer properties Reviewing the study findings, scientists caution against the idea of ‘miracle foods’ and suggest mushrooms can be a component of a diet that lowers cancer risks Eating two medium-sized mushrooms a day could lower […]

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Cytotoxic Effect of Oyster Mushroom Pleurotus ostreatus on Human Androgen-Independent Prostate Cancer PC-3 Cells

Twenty species of edible mushrooms and three purified mushroom polysaccharides were screened for their antitumor potential on human androgen-independent cancer PC-3 cells. A water-soluble extract (POE) prepared from the fresh oyster mushroom Pleurotus ostreatus produced the most significant cytotoxicity on PC-3 cells among the mushroom species tested. At the same time, POE induced a rapid […]

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Promising anticancer activity of polysaccharides and other macromolecules derived from oyster mushroom (Pleurotus sp.): An updated review

Abstract Cancer dominates among many causes of mortality worldwide. Traditional chemotherapeutic agents are powerful anti-cancer agents employed for treatment of this deadly disease. However, they are always associated with toxic side effects and immunosuppression making person more vulnerable to tumor relapse and fatalities. A promising alternative could be identification, isolation and transfer of naturally occurring […]

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